GAL UC-II Cartilage, Joint Complex (two months supply)

The most important ingredient of the UC-II® Cartilage complex is the raw material extracted from raw chicken brisket cartilage patented under the name UC-II®. As opposed to other cartilage extracts/collagens, it contains type II collagens in so-called non-denatured (raw) form, stabilized, so it would not denature or be digested even in the digestive system. This way it is capable to reach our lymphatic organs, the so-called Peyer’s patches located in our small intestine in unchanged (raw) form. As a result, it can influence our immune functions through our lymphatic system, and so it can stop attacking our own cartilage tissues, thus preventing the production of antibodies against them.

Such antibodies are not only produced in the case of autoimmune arthritis (Rheumatoid arthritis). When the cartilage surface of joints is damaged, worn as a result of incorrect movement (friction), or simply during more intense sports activities, a small part of collagen proteins II forming the cartilage gets denatured, which means that proteins foreign for the body are produced. to a greater or lesser extent, antibody production begins against them, which may cause chronic inflammation and other problems.

The above - and a number of other analyses - lead to the conclusion that the UC-II® is (very) efficient for all kinds of joint-related problems, especially in case of autoimmune joint-related problems.

40mg dose of UC-II® has been successfully used in a number of clinical tests. Although the 40mg dose may seem rather small, according to every analysis, this is the optimal dose for people. A higher dose is not better; on the contrary... The reason for this is that the effect of UC-II® on the immune system - as it is detailed above - is similar to that of a “protective vaccination”, via the lymphatic system instead of the conventional way (by transferring collagen peptides to the cartilage in the bloodstream, then by incorporating them into the cartilages + increasing the joint liquid).

In human clinical analyses, the dose of 40 mg UC-II® per day turned out to be significantly more efficient, than 1500mg Glucosamine HCI + 1200mg Chondroitin sulfate.

Although the essence of the product is to stop antibody production (to eliminate the autoimmune component of arthritis), and so the essence of the product is UC-II®, but we naturally also thought about building the joint + boosting the joint lubricant, i.e. the “conventional path”:

It also contains another chicken brisket cartilage extract patented under the name Chondractiv®. It contains type II collagens in partially hydrolyzed (pre-digested) form, but - among others - it also contains hyaluronic acid, chondroitin and other amino glycans, as parts of the natural, extra-cellular matrix of chicken cartilage, so they cannot compare to the isolated hyaluronic acid and chondroitin sulfate raw materials. This supplies building material and lubricant for the joints.

Our product also contains silicon extracted from organic bamboo shoots, as well as vitamin C. Both facilitate collagen synthesis, and according to clinical analyses, silicon has a beneficial effect in case of joint-related problems; furthermore, it is also known from the analyses that vitamin C further increases the positive impact of collagen peptides on the joints.

Our product also contains full-spectrum Curcuma extract called Curcugreen® (formerly Bio-Curcumin®, or BCM-95®), which is different from the conventional curcumin extracts, as it also contains the essential oil of the Curcuma root resulting in a minimum 7 times better absorption! On the other hand, it is significantly different not only from the conventional Curcuma extracts, but also from the Curcuma extracts with increased absorption capability, as CurcuGreen® is the only Curcuma extract in the world capable of increasing the useful (so-called free) curcumin level in the blood, and not its useless or less useful metabolites. CurcuGreen® is produced in 100 per cent using green energy (energy supplied by solar panels), extracted from Curcuma roots grown free of chemicals by the manufacturer on its own farm. Its effects are justified by numerous clinical examinations. (For more information refers to the description of our GAL Bio-Curcumin®+ and GAL Bio-Curcumin+ Forte products.

Although the quantity of Curcugreen® contained in the product is low (10mg), it is equal to approximately 1200mg Curcuma root powder. Furthermore, the timing for the evening, before going to bed has a significant role: according to a new analysis performed in 2018, in such case even a small dose of an anti-inflammation agent is much more efficient for rheumatic problems.

Made in the EU

Warnings

KEEP OUT OF REACH OF CHILDREN. DO NOT EXCEED RECOMMENDED DOSE.

If you are undergoing treatment for a medical condition or if you are pregnant or lactating, please consult your medical practitioner before introducing supplementary foods to your normal routine. The dietary supplement should not be used as a substitute for a varied and balanced diet or a healthy lifestyle. Store tightly closed in a cool and dry place.

References:

UC-II®:
Lugo JP, et al. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J. 2016;15:14. 
Lugo JP, et al. Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. J lnt Soc Sports Nutr. 2013;10:48. 
Lugo JP, et al. Efficacy and tolerability of an undenatured type ll collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J. 2016;15:14. 
Lugo JP, et al. Undenatured type ll collagen (UC-ll®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. J lnt Soc Sports Nutr. 2013;10:48. 
Crowley DC, et al. Safety and efficacy of undenatured type ll collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009;6:312-321. 
Lugo JP, et al. Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. J lnt Soc Sports Nutr. 2013;10:48. 
Lugo JP, et al. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J. 2016;15:14. 
Lugo JP, et al. Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. J lnt Soc Sports Nutr. 2013;10:48. 
Bagi C.M. Osteoarthritis - Opportunities for nonsurgical therapies. Presented at 8th International Conference of Orthopedic Surgeons and Rheumatology, March 22-23, 2017 Rome, Italy
Marone PA, et al. Safety and toxicological evaluation of undenatured type II collagen. Toxicol Mech Meth. 2010;20:175-189.
Circadian and inflammation reduction (increased effect in case of evening intake):
Cutolo M.: Circadian rhythms and rheumatoid arthritis. Joint Bone Spine. 2019 May;86(3):327-333. doi: 10.1016/j.jbspin.2018.09.003. Epub 2018 Sep 15.
Other: Examine.com